For Qualified Researchers
Research Use
Policy.
All products are strictly for in-vitro laboratory research and scientific experimentation only. By purchasing, you confirm you meet the requirements below.
Research Use Disclaimer
All products are intended strictly for in-vitro laboratory research and experimentation only. Not for human or animal consumption, diagnostic, or therapeutic use. Not for use in food, drugs, medical devices, or cosmetics. These products have not been evaluated by any regulatory authority and are not intended to diagnose, treat, cure, or prevent any disease.
Purchaser Qualifications
21+ years of age
Purchaser must be at least 21 years old.
Qualified researcher
Research professional, accredited institution, licensed laboratory, or documented independent research capacity.
Regulatory compliance
Products must be handled in compliance with applicable local, state, and federal regulations by trained professionals in controlled laboratory environments.
Sole responsibility
Purchaser assumes full responsibility for the lawful, safe, and appropriate use of all products.
No liability
AKRO Research assumes no liability for any misuse, improper handling, or unauthorized use of products.
Handling & Reconstitution
All compounds are supplied as lyophilized (freeze-dried) powder in sealed, sterile vials. Bacteriostatic water for reconstitution is sold separately.
AKRO Research does not provide reconstitution guidance or dosing information. Researchers are solely responsible for determining appropriate reconstitution protocols for their specific in-vitro research application.
Storage Instructions
−20°C
Long-Term
Freezer
2–8°C
Short-Term
Refrigerator
Ambient
In Transit
Room temp safe
2–8°C
Reconstituted
Use promptly
Protect from light, moisture, and repeated freeze-thaw cycles. Discard any reconstituted solution showing discoloration or signs of contamination.
No medical claims. These products have not been evaluated by the FDA or any other regulatory authority. They are not drugs and are not intended to diagnose, treat, cure, or prevent any disease or medical condition. All purchasers are responsible for ensuring compliance with applicable laws in their jurisdiction.
Amino Acid Sensitivity
Not all residues are created equal
Some amino acids are inherently more reactive. Knowing which residues your peptide contains helps predict its stability profile.
| Residue | Primary Degradation Risk | Storage Implication |
|---|---|---|
| Cysteine (Cys) | Oxidation Oxidation — disulfide bond formation; sulfoxide/sulfone in presence of O₂ | Most sensitive residue. Minimize oxygen exposure. -80°C recommended for long-term. |
| Methionine (Met) | Oxidation Oxidation — sulfoxide formation, leading to loss of bioactivity | Avoid oxidizing conditions. Monitor for activity changes over time. |
| Tryptophan (Trp) | Oxidation + Photo Oxidation + Photodegradation — kynurenine formation; light-induced cleavage | Amber/foil-wrapped vials critical. Avoid UV light at bench. |
| Asparagine (Asn) | Deamidation Deamidation — conversion to aspartate, altering charge and structure | Especially sensitive at neutral-basic pH when reconstituted. Keep at pH 4–6 if possible. |
| Glutamine (Gln) | Deamidation Deamidation — slower than Asn but still significant over time | Store lyophilized when possible. Monitor reconstituted solutions closely. |
| Aspartate (Asp) | Hydrolysis Hydrolysis — Asp-Pro peptide bonds especially susceptible to acid cleavage | Avoid acidic reconstitution buffers. -20°C or colder for storage. |
| Histidine (His) | Oxidation Oxidation — imidazole ring oxidation in reactive oxygen environments | Protect from oxidizing agents. Lyophilized form highly preferred. |
Best Practices
Preserving integrity at your bench
What you do after delivery is just as important as how the peptide was made. Follow these steps to maximize shelf life and potency.
Always let sealed vials warm to room temperature before opening
Moving a cold vial directly from the freezer to a warm room creates condensation inside the vial the moment it is opened. That moisture immediately begins to degrade the lyophilized peptide. Let the sealed vial equilibrate to room temperature (15–30 minutes) before opening — never skip this step.
Aliquot before freezing
Divide reconstituted peptides into single-experiment aliquots before placing in the freezer. This eliminates freeze-thaw cycling entirely — each aliquot is thawed exactly once and discarded after the experimental session.
Store under desiccant
Even sealed vials benefit from desiccant in the storage container. When working with open or partially used vials, store under argon or nitrogen purge with fresh desiccant to minimize humidity exposure.
Use amber vials or foil wrap
Peptides containing Trp, Phe, or Tyr are sensitive to UV and visible light. Store in amber glass or foil-wrapped vials at all times — even brief bench exposure can initiate cumulative photodegradation.
Match solvent to peptide chemistry
Most peptides are most stable near neutral pH (6–7). Acidic or basic solvents accelerate specific degradation pathways. Asp-containing peptides are especially sensitive to acidic conditions.
Label with reconstitution date
Reconstituted peptides stored at 2–8°C are generally stable for up to 6 weeks. Date your vials at reconstitution and discard after this window — degradation is often invisible and does not change clarity or color.
Minimize bench time during active use
Return peptide solutions to cold storage promptly after withdrawing your working aliquot. Ambient temperature exposure accumulates — a solution left on the bench during a 4-hour protocol experiences meaningfully more degradation.