PT-141
Bremelanotide
Research Highlights
Central-acting MC3R/MC4R agonist — distinct mechanism from PDE5 inhibitors
Studied for sexual arousal and libido in both male and female research models
Derived from α-MSH with cyclic structure for enhanced metabolic stability
Sequence: Ac-Nle-Asp(1)-His-D-Phe-Arg-Trp-Lys(1)
18,100+ monthly searches — high-demand research compound
Lyophilized powder — reconstitution with bacteriostatic water or a suitable solvent is required prior to in-vitro experimental use. BAC Water is available separately in our Solvents category.
PT-141 (Bremelanotide) is a synthetic cyclic heptapeptide derived from alpha-melanocyte-stimulating hormone (α-MSH)1. Unlike peripheral vasodilators, PT-141 acts centrally via melanocortin receptor agonism (MC3R and MC4R)2, making it a distinct research tool for studying sexual arousal pathways2, neuroendocrine signalling, and melanocortin system modulation in preclinical models.
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